Research progress of effects and mechanisms of paeony and total glucosides of paeony in treatment of immune-associated dermatoses

doi:10. 3969/ j. issn. 1006-7795. 2024. 01. 001

Abstract

Abstract: Pharmacological studies have shown that white paeony has anti-inflammatory,immunomodulatory,hepatoprotective,and analgesic effects. In clinical practice, paeony and total glucosides of paeony are often used to treat autoimmune diseases. As the anti-inflammatory, immune-modulating and anti-oxidizing mechanisms of paeony and total glucosides of paeony are gradually understood,their clinical applications in immune-related and inflammatory skin diseases have been continuously expanded. The mechanisms such as anti-oxidation play an important role in enhancing efficacy,attenuating toxicity,and reducing disease recurrence rates. This article reviews the research progresses on the effects and mechanisms of paeony and total glucosides of paeony in the treatment of immune-related and inflammatory skin diseases, to provide a basis for in-depth research.

Key words: paeony, total glucosides of paeony, autoimmune skin disease, mechanism study

CLC Number:

Yang Yang, Chen Ruixuan, Min Li, Ma Zhijie, Mei Xueling, . Research progress of effects and mechanisms of paeony and total glucosides of paeony in treatment of immune-associated dermatoses[J]. Journal of Capital Medical University, doi: 10. 3969/ j. issn. 1006-7795. 2024. 01. 001.

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